Subgroup Analysis of Topical Tranexamic Acid in Primary Total Hip Arthroplasty

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Intravenous versus topical tranexamic acid in primary total hip replacement

BACKGROUND As the prevalence of total hip arthroplasty (THA) is increasing, it is usually associated with considerable blood loss. Tranexamic acid (TXA) has been reported to reduce perioperative blood loss in hip joint arthroplasty. But the best route of TXA administration continues to be controversial. So, we conducted a meta-analysis that integrated all data from the 7 included trials to comp...

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The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis

BACKGROUND Topical tranexamic acid (TXA) has been shown to be effective in reducing blood loss and the need for transfusion after total knee arthroplasty. However, the effectiveness of topical TXA use in total hip arthroplasty (THA) still remains unclear. The purpose of this meta-analysis is to examine the safety and efficacy of topical use of TXA following THA. HYPOTHESIS Topical TXA reduces...

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Combined application versus topical and intravenous application of tranexamic acid following primary total hip arthroplasty: a meta-analysis

BACKGROUND The use of intravenous (IV) or topical tranexamic acid (TXA) in total hip arthroplasty has been proven to be effective and safe in total hip arthroplasty. However, which of these two administration routes is better has not been determined. The combined administration of TXA has been used in total knee arthroplasty with satisfactory results. We hypothesized that combined application o...

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Meta-analysis of Intravenous Tranexamic Acid in Primary Total Hip Arthroplasty.

Previous meta-analyses established that tranexamic acid confers benefits when used during total hip arthroplasty (THA). However, 2 of these meta-analyses included a variety of routes of administration of tranexamic acid in THA (topical, intravenous, oral, and intra-articular), another meta-analysis included a variety of antifibrinolytic drugs (not restricted to a single drug), and the final met...

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Intra-articular administration of tranexamic acid in total hip arthroplasty.

PURPOSE To evaluate the effectiveness of intraarticular tranexamic acid (TXA) in reducing blood loss and the need for blood transfusion during total hip arthroplasty (THA). METHODS Records of 19 men and 31 women aged 46 to 83 (mean, 62) years who underwent primary THA with intra-articular administration of TXA were reviewed. They were compared with a matched cohort of 17 men and 33 women aged...

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ژورنال

عنوان ژورنال: Reconstructive Review

سال: 2015

ISSN: 2331-2270,2331-2262

DOI: 10.15438/rr.5.1.80